EVALUATE THE INFLUENCES OF BUFFALO MILK ON HYPERCHOLESTEROLEMIA AND HYPERLIPIDEMIA IN MALE ALBINO RATS

Hyperlipidemia is a condition of elevated lipid level in blood.
Hyperlipidemia is a major cause of atherosclerosis which
atherosclerosis related conditions like coronary heart disease (CHD),
ischemic cerebrovascular disease, peripheral vascular disease and
pancreatitis1-2. The increase in lipids like low density lipoproteins
(LDL-c), cholesterol (esters derivatives) and triglycerides are mainly
responsible for this condition. This present study was designed to
explore the efficiency of the buffalo milk dose in controlling
hyperlipidemia . 25 male albino rats were used in this investigation
which divided into five groups, The first one was used as a normal
health control group (G1), while the remaining four groups were
feeding with high-fat diet in order to induce hyperlipidemia. The
hyperlipidemic group was divided into hyperlipidemic control group
(G2), groups of the treated buffalo milk according to the amount of
buffalo milk divided into 1 ml (G 3), 1.5 ml (G 4) and 2 ml (G 5) for
100 g body weight, and the period of the study was for 7 weeks. Blood
lipid profile, liver function and kidneys function was measured at the
end of the experimental period.
This study revealed that there was a significant changes in blood
parameters of treated groups in comparison with the other group
without any treatment. The buffalo milk group exhibited a significant
improvement in lipid profile compared to hyperlipidemic control
animals. This study documented the efficiency of the buffalo milk in
EVALUATE THE INFLUENCES OF BUFFALO336
controlling of hyperlipidemia and improvement of kidneys function
and liver function. So an extensive research on the buffalo milk is still
needed to demonstrate this mechanism.